Abstract

Polycystic ovary syndrome (PCOS), endometriosis, and uterine fibroids are highly prevalent gynecologic conditions that often lead to pelvic pain, menstrual irregularities, and infertility. While standard treatment relies on hormonal therapy and surgery, there is growing interest in integrative, nonpharmacologic approaches, including OMT. This review summarizes current diagnostic and treatment strategies for PCOS, fibroids, and endometriosis, and explores the role of OMT in their management. 

A targeted PubMed and Cochrane Library search identified 26 relevant studies for PCOS, 18 for fibroids, 19 for endometriosis, and 8 for osteopathic interventions. Evidence supports lifestyle changes and medications like metformin and letrozole for PCOS, while uterine fibroids are managed surgically or with newer interventional and hormonal options. Endometriosis treatment includes medical suppression and excision, with emerging diagnostic biomarkers and imaging tools. 
OMT shows promise in reducing pelvic pain and enhancing quality of life, particularly in endometriosis and PCOS, by addressing musculoskeletal and autonomic dysfunction. Although direct evidence remains limited, osteopathic care may complement conventional treatment. Further research is warranted to define its clinical utility in multidisciplinary gynecologic care. 


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