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Review Articles

2-8
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Fertility awareness-based methods of family planning: A review of effectiveness for avoiding pregnancy using SORT

Each year, over three-fourths of the women of reproductive age in the United States seek family planning services from primary care clinicians. Women and their doctors should be informed of all effective family planning options and their respective effects on a woman's reproductive healt...
9-16
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Office IgE-mediated environmental allergy evaluation and treatment

Environmental allergens that induce a type I immune hypersensitivity present a widespread and significant reduction in the quality of life for our patients while imposing a stifling cost upon health care and the economy. A prompt, accurate clinical diagnosis with an appropriate managemen...
17-23
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An osteopathic approach to reduction of readmissions for neonatal jaundice

Jaundice is a potentially life-threatening condition that continues to affect at-risk newborns, accounting for continued hospital readmissions. As family physicians, we should be cognizant of neonates who may be at risk for jaundice, including those with pathologic jaundice as well as ne...
24-26
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A unique case of polyostotic Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a relatively rare dendritic cell disorder with an unclear etiology. The incidence is 2:1 million and it is most commonly seen in children from 5 to 10 years of age. The diagnosis is confirmed by biopsy with treatment options varying from simple obse...

Supplement

29-30
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You make the choice, clinical decision making in diabetes: Use of GLP-1 receptor agonists in clinical practice

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33-42
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Diabetes clinical decision-making in patients at risk: Taking patient complexity into account

The sheer numbers of patients with type 2 diabetes, a chronic illness with multifactorial pathophysiology, common comorbidities, exacerbated by an obesity epidemic and a lack of specialists to care for them may seem daunting. However, new treatment options and treatment guidelines that t...
43-50
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Evidence from randomized clinical trials demonstrating improved glycemic control with GLP-1 receptor agonists when used with other agents vs other combination therapy strategies

Incretin-based therapies include glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 (DPP-4) based therapies. Both classes of agents are predicated on the knowledge that GLP-1, a gut-derived hormone, plays a major role in glucose homeostasis, a fact that has been...
51-57
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Enhancing treatment success with incretin-based therapies: A comprehensive approach to the patient with diabetes

Adding glucagon-like peptide-1 (GLP-1) receptor agonists to insulin therapy for patients with type 2 diabetes mellitus (T2DM): why and how patients with T2DM who progress to insulin therapy usually do so by starting with a single injection of a long-acting insulin analog, added to oral a...